megatomi.com - An Overview
megatomi.com - An Overview
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Our new Obvious+ tissue clearing system is the only technique that delipidates samples without any transform in morphology and with negligible impact on structural integrity.
Our transform-critical SmartBatch+ system combines electrophoretic tissue clearing and immunolabeling into a single large-throughput unit.
Antibodies may just take months to diffuse via just a few millimeters of tissue, with a steep labeling gradient from floor to Main.
Megatome is made for precision: the blade vibrates at the next frequency and larger amplitude vary than other microtomes, and incorporates a special deflection Manage system.
SE uses a rotational electrical industry to disperse highly electromobile molecules (for instance antibodies or surfactant micelles) all through a porous sample without the need of detrimental electrically charged structures inside the tissue. This enables two-4 working day clearing of intact organs,
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Megatome is a novel microtome which allows for top-precision sectioning of a megatomi.com variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue destruction and knowledge decline.
eFLASH is often a swift tissue labeling procedure that permits for uniform entire-organ staining in 20 rounds of labeling.
Completely delipidate entire mouse brains or comparably sized samples in just one day with SmartBatch+, or in a single 7 days with our passive clearing package.
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Defend avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, shielding specimens for a number of rounds of processing.
Leverage the Very clear+ tissue clearing process, as well as eFLASH and patented stochastic electrotransport technologies, to fast very clear and label full organs. Essential highlights and features incorporate:
Our novel SHIELD tissue preservation procedure types intramolecular bonds applying polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.